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Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid
《医学前沿(英文)》 2021年 第15卷 第6期 页码 887-902 doi: 10.1007/s11684-021-0879-9
关键词: microRNAs monocarboxylate transporter 1 motor training subarachnoid hemorrhage white matter injury
Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong
《医学前沿(英文)》 2021年 第15卷 第1期 页码 125-138 doi: 10.1007/s11684-019-0725-5
关键词: Parkinson’s disease diffusion tensor imaging fractional anisotropy meta-analysis anisotropic effect size–signed differential mapping
Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT
《化学科学与工程前沿(英文)》 2012年 第6卷 第2期 页码 216-223 doi: 10.1007/s11705-012-1289-y
关键词: recombinant protein polyclonal antibody label-free biosensor impedance white spot syndrome virus (WSSV)
Bile duct injury repair — earlier is not better
null
《医学前沿(英文)》 2015年 第9卷 第4期 页码 508-511 doi: 10.1007/s11684-015-0418-7
Bile duct injury is a common complication of cholecystectomy. The timing of bile duct injury repair remains controversial. A recent review conducted in France reported 39% complications and 64% failure after immediate repair in 194 patients compared with 14% complications and 8% failure after late repair in 133 patients. A national review of 139 consecutive early repairs conducted at five hepatopancreaticobiliary centers in Denmark reported 4% mortality, 36% morbidity, and 42 restrictures (30%) at a median follow-up of 102 months, and only 64 patients (46%) demonstrated uneventful short-term and long-term outcomes. Most patients with bile duct injury present with bile leak and sepsis; thus, early repair is not recommended. Percutaneous drainage of bile and endoscopic stenting are the mainstays of treatment of bile leak because they convert acute bile duct injury into a controlled external biliary fistula. The ensuing benign biliary stricture should be repaired by a biliary surgeon after a delay of 4–6 weeks once the external biliary fistula has closed.
关键词: bile duct injury cholecystectomy laparoscopic cholecystectomy
Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG
《农业科学与工程前沿(英文)》 2014年 第1卷 第4期 页码 299-306 doi: 10.15302/J-FASE-2014040
关键词: Silky Fowl White Leghorn melanoblast migration gene expression
Risk factors of prognosis after acute kidney injury in hospitalized patients
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《医学前沿(英文)》 2017年 第11卷 第3期 页码 393-402 doi: 10.1007/s11684-017-0532-9
The risk factors, especially laboratory indicators, of prognosis after acute kidney injury (AKI) remain unclear. We conducted a retrospective survey of Chinese People’s Liberation Army General Hospital from January 1, 2012 to December 31, 2012 according to the AKI diagnosis standard issued by Kidney Disease Improving Global Outcomes. The epidemiological features and factors influencing hospital mortality and renal function recovery were evaluated through logistic regression analysis. Among 77 662 cases of hospitalized patients, 1387 suffered from AKI. The incidence rate and mortality of AKI were 1.79% and 14.56%, respectively. Multivariate logistic regression analysis revealed that high AKI stage, age greater than 80 years, neoplastic disease, low cardiac output, increased white blood cell count, and decreased platelet count and serum albumin levels were the risk factors affecting the mortality of AKI patients. Conversely, body mass index between 28 and 34.9 was a protective factor. Increased AKI stage, tumor disease, post-cardiopulmonary resuscitation, and RRT were the risk factors of renal function recovery upon discharge. In addition to traditional risk factors, white blood cell count, platelet count, albumin, and BMI were the predictors of the mortality of AKI patients. No laboratory indicators were found to be the risk factors of renal function recovery in AKI patients.
Min-Ho CHEY, Jae-Ung KIM
《结构与土木工程前沿(英文)》 2012年 第6卷 第3期 页码 267-280 doi: 10.1007/s11709-012-0170-x
关键词: tuned mass damper parametric optimization passive control white noise earthquake excitation
INDIAN PERSPECTIVE: SUSTAINABILITY OF BT COTTON IS A MATTER OF CONCERN NOW!
《农业科学与工程前沿(英文)》 2022年 第9卷 第1期 页码 146-149 doi: 10.15302/J-FASE-2021415
Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels
Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA
《农业科学与工程前沿(英文)》 2019年 第6卷 第2期 页码 197-205 doi: 10.15302/J-FASE-2018245
The present study was designed to investigate the protective effects of leonurine, a compound purified from that is active on ischemic rat behavior and cortical neurons, and explore the underlying mechanism. The general rat activity, cortical neuron morphology, superoxide dismutase (SOD), malondialdehyde (MDA), -aminobutyric acid (GABA) and glutamate decarboxylase 67 (GAD67) levels were measured. We found leonurine significantly improve the general activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemia. Moreover, serum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemia group. In addition, GABA content in the cerebral cortex was significantly greater in high-dose leonurine group. Correspondingly, GAD67 protein level coincided with the GABA level. Taken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative and anti-excitotoxicity effects by targeting GABA and leonurine might become a useful adjuvant neuroprotective agent.
Progress and perspectives of neural tissue engineering
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《医学前沿(英文)》 2015年 第9卷 第4期 页码 401-411 doi: 10.1007/s11684-015-0415-x
Traumatic injuries to the nervous system lead to a common clinical problem with a quite high incidence and affect the patient’s quality of life. Based on a major challenge not yet addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissue engineering has emerged, grown, and attracted increasing interest. This review provides a brief summary of the recent progress in the field, especially in combination with the research experience of the author’s group. Several important aspects related to tissue engineered nerves, including the theory on their construction, translation into the clinic, improvements in fabrication technologies, and the formation of a regenerative environment, are delineated and discussed. Furthermore, potential research directions for the future development of neural tissue engineering are suggested.
《环境科学与工程前沿(英文)》 2023年 第17卷 第11期 doi: 10.1007/s11783-023-1743-8
● Microplastics (MPs) undergo photoaging in natural water under light irradiation.
关键词: Microplastics Photoaging Dissolved organic matter ROS generation
《医学前沿(英文)》 2021年 第15卷 第5期 页码 750-766 doi: 10.1007/s11684-021-0839-4
关键词: particulate matter 2.5 sirtuin 2 p65 airway inflammation bronchial hyperresponsiveness triptolide
reduces IgE binding ability of allergenic egg white proteins
Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU
《农业科学与工程前沿(英文)》 2018年 第5卷 第3期 页码 373-381 doi: 10.15302/J-FASE-2018210
Egg white proteins are one of the major allergens. The objective of this study was to investigate the effect of Aspergillus oryzae cultivation on IgE binding ability of egg white proteins. Effect of A. oryzae on egg white proteins was determined using ninhydrin method, SDS-PAGE, ELISA, fluorescence FITC labeling, MALDI-TOF-MS and LC-MS/MS analysis. Adding mycelium of A. oryzae ATCC 1011 and 16868 substantially reduced the IgE binding ability of acidified egg white after 24 h incubation. The binding capacity of egg white proteins to IgE in plasma from four egg allergy patients was almost completely lost after incubation with mycelium of ATCC 16868. Results from SDS-PAGE, free amino acid analysis, MALDI-TOF-MS and LC-MS/MS indicated that there was no substantial protein degradation during incubation. Therefore, the reduction of IgE binding ability of egg white proteins during A. oryzae treatment was probably due to a loss of ~1700 Da mass including a fragment of the ovomucoid N terminus.
关键词: Aspergillus oryzae egg allergy egg white proteins IgE-binding ability ovomucoid
WANG Lin, LIU Yalan, XU Jianbo, TIAN Yuan, WU Heshui
《医学前沿(英文)》 2008年 第2卷 第2期 页码 182-185 doi: 10.1007/s11684-008-0034-x
Effect of oxytocin on gastric ischemia-reperfusion injury in rats
ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming
《医学前沿(英文)》 2007年 第1卷 第4期 页码 433-437 doi: 10.1007/s11684-007-0085-4
关键词: control significant difference surgical statistical significance Sprague-Dawley
标题 作者 时间 类型 操作
Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid
期刊论文
Altered white matter microarchitecture in Parkinson’s disease: a voxel-based meta-analysis of diffusion
Xueling Suo, Du Lei, Wenbin Li, Lei Li, Jing Dai, Song Wang, Nannan Li, Lan Cheng, Rong Peng, Graham J Kemp, Qiyong Gong
期刊论文
Production of a polyclonal antibody to the VP26 nucleocapsid protein of white spot syndrome virus (wssv
Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT
期刊论文
A microarray study of altered gene expression during melanoblasts migration in normal pigmented White
Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG
期刊论文
control of structural responses using an optimal passive tuned mass damper under stationary Gaussian white
Min-Ho CHEY, Jae-Ung KIM
期刊论文
Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels
Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA
期刊论文
Photoaging mechanism of microplastics: a perspective on the effect of dissolved organic matter in natural
期刊论文
Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating
期刊论文
reduces IgE binding ability of allergenic egg white proteins
Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU
期刊论文
Protective effect of N-acetylcysteine against lipopolysaccharide injury in hepatocytes of neonatal mice
WANG Lin, LIU Yalan, XU Jianbo, TIAN Yuan, WU Heshui
期刊论文